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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q96LD8	SENP8	T13928	Literature-reported Target
2	Q8TDD5	MCOLN3	T14241	Literature-reported Target
3	O75908	SOAT2	T14463	Clinical trial target	Adrenal cancer	[ICD-11: 2D11]	Neoplasms
4	Q15661	TPSAB1	T14558	Successful Target	Fungal infection Solid tumour/cancer	[ICD-11: 1F29-1F2F] [ICD-11: 2A00-2F9Z]	Certain infectious or parasitic diseases Neoplasms
5	P04626	ERBB2	T14597	Successful Target	Breast cancer Lung cancer Prostate cancer	[ICD-11: 2C60-2C6Y] [ICD-11: 2C25] [ICD-11: 2C82]	Neoplasms Neoplasms Neoplasms
6	Q99755	PIP5K1A	T14630	Literature-reported Target
7	Q96EB6	SIRT1	T14731	Clinical trial target	Rheumatoid arthritis Systemic sclerosis Vasculitis	[ICD-11: FA20] [ICD-11: 4A42] [ICD-11: 4A44]	Diseases of the musculoskeletal system or connective tissue Diseases of the immune system Diseases of the immune system
8	P47712	PLA2G4A	T14834	Clinical trial target	Atopic eczema	[ICD-11: EA80]	Diseases of the skin
9	Q92851	CASP10	T14894	Patented-recorded Target
10	Q16739	UGCG	T14908	Successful Target	Lysosomal disease Metabolic disorder	[ICD-11: 5C56] [ICD-11: 5C50-5D2Z]	Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases
11	Q07820	MCL1	T14912	Clinical trial target	Acute myeloid leukaemia Malignant haematopoietic neoplasm Mature B-cell lymphoma Melanoma Multiple myeloma Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2B33] [ICD-11: 2A85] [ICD-11: 2C30] [ICD-11: 2A83] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms
12	Q02224	CENPE	T14945	Literature-reported Target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
13	O14786	NRP1	T15023	Successful Target	Retinopathy	[ICD-11: 9B71]	Diseases of the visual system
14	P49238	CX3CR1	T15033	Literature-reported Target
15	P08833	IGFBP1	T15048	Literature-reported Target
16	P00338	LDHA	T15053	Literature-reported Target
17	Q05397	PTK2	T15068	Clinical trial target	Metastatic tumour Ovarian cancer Pancreatic cancer Peritoneal cancer Pulmonary hypertension Solid tumour/cancer	[ICD-11: 2D50-2E2Z] [ICD-11: 2C73] [ICD-11: 2C10] [ICD-11: 2C51] [ICD-11: BB01] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms Diseases of the circulatory system Neoplasms
18	O43175	PHGDH	T15139	Literature-reported Target
19	Q9UN88	GABRQ	T15161	Literature-reported Target
20	P11597	CETP	T15334	Clinical trial target	Arterial occlusive disease Cardiovascular disease Hyper-lipoproteinaemia Myocardial infarction	[ICD-11: BD40] [ICD-11: BA00-BE2Z] [ICD-11: 5C80] [ICD-11: BA41-BA43]	Diseases of the circulatory system Diseases of the circulatory system Endocrine, nutritional or metabolic diseases Diseases of the circulatory system
21	P21730	C5AR1	T15439	Successful Target	Vasculitis	[ICD-11: 4A44]	Diseases of the immune system
22	P34995	PTGER1	T15497	Clinical trial target	Thrombosis	[ICD-11: DB61-GB90]	Diseases of the digestive system
23	Q8NCG7	DAGLB	T15509	Literature-reported Target
24	P41235	HNF4A	T15514	Literature-reported Target
25	Q92959	SLCO2A1	T15518	Patented-recorded Target