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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P05121	SERPINE1	T15556	Clinical trial target	Asthma Thrombosis	[ICD-11: CA23] [ICD-11: DB61-GB90]	Diseases of the respiratory system Diseases of the digestive system
2	P47898	HTR5A	T15571	Successful Target	Pituitary gland disorder	[ICD-11: 5A60-5A61]	Endocrine, nutritional or metabolic diseases
3	P55786	NPEPPS	T15610	Clinical trial target	Acute myeloid leukaemia Myelodysplastic syndrome	[ICD-11: 2A60] [ICD-11: 2A37]	Neoplasms Neoplasms
4	P22459	KCNA4	T15665	Literature-reported Target
5	Q9UQ81	MCH5	T15700	Patented-recorded Target	Diabetes mellitus Solid tumour/cancer	[ICD-11: 5A10] [ICD-11: 2A00-2F9Z]	Endocrine, nutritional or metabolic diseases Neoplasms
6	P04637	TP53	T15739	Clinical trial target	Lip/oral cavity/pharynx neoplasm Ovarian dysfunction Transplant rejection	[ICD-11: 2B6E] [ICD-11: 5A80] [ICD-11: NE84]	Neoplasms Endocrine, nutritional or metabolic diseases Injury, poisoning or certain other consequences of external causes
7	Q9UIF8	BAZ2B	T15745	Literature-reported Target
8	O14649	KCNK3	T15795	Clinical trial target	Obstructive sleep apnoea	[ICD-11: 7A41]	Sleep-wake disorders
9	Q9NRG4	SMYD2	T15797	Preclinical target	Lung cancer Solid tumour/cancer	[ICD-11: 2C25] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
10	P42680	TEC	T15848	Patented-recorded Target
11	P11172	UMPS	T15851	Literature-reported Target
12	Q6V1X1	DPP8	T15855	Clinical trial target	Neutropenia	[ICD-11: 4B00]	Diseases of the immune system
13	P24158	PRTN3	T15882	Clinical trial target	Malignant haematopoietic neoplasm Myocardial infarction	[ICD-11: 2B33] [ICD-11: BA41-BA43]	Neoplasms Diseases of the circulatory system
14	P32246	CCR1	T16016	Clinical trial target	Diabetes mellitus Rheumatoid arthritis	[ICD-11: 5A10] [ICD-11: FA20]	Endocrine, nutritional or metabolic diseases Diseases of the musculoskeletal system or connective tissue
15	P16050	ALOX15	T16042	Patented-recorded Target
16	P29475	NOS1	T16117	Clinical trial target	Headache Migraine	[ICD-11: 8A80-8A84] [ICD-11: 8A80]	Diseases of the nervous system Diseases of the nervous system
17	P40238	MPL	T16156	Successful Target	Thrombocytopenia	[ICD-11: 3B64]	Diseases of the blood or blood-forming organs
18	P13501	CCL5	T16263	Clinical trial target	Diabetes mellitus	[ICD-11: 5A10]	Endocrine, nutritional or metabolic diseases
19	Q13526	PIN1	T16308	Clinical trial target	Lung cancer	[ICD-11: 2C25]	Neoplasms
20	P18031	PTPN1	T16347	Clinical trial target	Acute diabete complication Breast cancer Obesity Type 2 diabetes mellitus	[ICD-11: 5A2Y] [ICD-11: 2C60-2C6Y] [ICD-11: 5B80-5B81] [ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases Neoplasms Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases
21	P49327	FASN	T16514	Successful Target	concerning food/fluid intake symptom	[ICD-11: MG43]	Symptoms, signs or clinical findings, not elsewhere classified
22	Q15391	P2RY14	T16555	Literature-reported Target
23	Q86V86	PIM3	T16596	Patented-recorded Target
24	P30872	SSTR1	T16633	Successful Target	Cushing syndrome Stomach cancer	[ICD-11: 5A70] [ICD-11: 2B72]	Endocrine, nutritional or metabolic diseases Neoplasms
25	O75907	DGAT1	T16688	Successful Target	Hyper-lipoproteinaemia	[ICD-11: 5C80]	Endocrine, nutritional or metabolic diseases