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List of therapeutic targets associated diseases

Showing 1 to 25 of 1414 | 1 2 3 Next » Last

Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	O14976	GAK	T00043	Target	Rheumatoid arthritis	[ICD-11: FA20]	Diseases of the musculoskeletal system or connective tissue
2	Q5VT25	CDC42BPA	T00075	Literature-reported Target
3	P04632	CAPNS1	T00099	Target	COVID-19	[ICD-11: 1D6Y]	Certain infectious or parasitic diseases
4	P09917	ALOX5	T00140	Successful Target	Asthma Filariasis Thrombocytopenia	[ICD-11: CA23] [ICD-11: 1F66] [ICD-11: 3B64]	Diseases of the respiratory system Certain infectious or parasitic diseases Diseases of the blood or blood-forming organs
5	Q00987	MDM2	T00176	Clinical trial target	Acute myeloid leukaemia Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
6	P20393	NR1D1	T00254	Preclinical target	Cardiomyopathy Postoperative inflammation Solid tumour/cancer	[ICD-11: BC43] [ICD-11: 1A00-CA43] [ICD-11: 2A00-2F9Z]	Diseases of the circulatory system Postoperative inflammation Neoplasms
7	P30532	CHRNA5	T00299	Literature-reported Target
8	O60235	TMPRSS11D	T00302	Literature-reported Target
9	O60885	BRD4	T00407	Target
10	O00398	P2RY10	T00488	Literature-reported Target
11	Q14654	KCNJ11	T00820	Literature-reported Target
12	P41279	MAP3K8	T00852	Clinical trial target	Indeterminate colitis	[ICD-11: DD72]	Diseases of the digestive system
13	P25024	CXCR1	T00884	Successful Target	Pain	[ICD-11: MG30-MG3Z]	Symptoms, signs or clinical findings, not elsewhere classified
14	P49019	HCAR3	T00890	Clinical trial target	Cardiovascular disease Dyslipidemia Hyper-lipoproteinaemia Psoriasis	[ICD-11: BA00-BE2Z] [ICD-11: 5C80-5C81] [ICD-11: 5C80] [ICD-11: EA90]	Diseases of the circulatory system Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases Diseases of the skin
15	Q02156	PRKCE	T00895	Successful Target	Anxiety disorder Malaria	[ICD-11: 6B00-6B0Z] [ICD-11: 1F40-1F45]	Mental, behavioural or neurodevelopmental disorders Certain infectious or parasitic diseases
16	Q9UPP1	PHF8	T00933	Literature-reported Target
17	Q86U86	PBRM1	T00973	Literature-reported Target
18	O75460	ERN1	T01003	Clinical trial target	Breast cancer	[ICD-11: 2C60-2C6Y]	Neoplasms
19	Q9H7Z7	PTGES2	T01037	Target
20	Q9H2J7	SLC6A15	T01138	Target
21	Q15904	ATP6AP1	T01211	Target
22	Q9H773	DCTPP1	T01249	Target
23	Q9NY57	STK32B	T01255	Literature-reported Target
24	Q9Y5Z0	BACE2	T01280	Clinical trial target	Urinary system clinical symptom	[ICD-11: MF8Y]	Symptoms, signs or clinical findings, not elsewhere classified
25	Q7KZI7	MARK2	T01396	Target