List of therapeutic targets associated diseases


                                                                                      Sr. No. Uniprot ID Gene name TTD ID Target type Disease name ICD-11 Disease class
                                                                                      1Q96RJ0TAAR1T99524Successful Target
                                                                                    • Attention deficit hyperactivity disorder
                                                                                    • Focal/segmental autonomic disorder
                                                                                    • Narcolepsy
                                                                                    • [ICD-11: 6A05]
                                                                                    • [ICD-11: 8D8A]
                                                                                    • [ICD-11: 7A20]
                                                                                    • Mental, behavioural or neurodevelopmental disorders
                                                                                    • Diseases of the nervous system
                                                                                    • Sleep-wake disorders
                                                                                      • 2P30837ALDH1B1T99641Successful Target
                                                                                    • Substance abuse
                                                                                    • [ICD-11: 6C40]
                                                                                    • Mental, behavioural or neurodevelopmental disorders
                                                                                      • 3P24046GABRR1T99665Literature-reported Target
                                                                                      4P63165SUMO1T99765Preclinical target
                                                                                    • Acute myeloid leukaemia
                                                                                    • [ICD-11: 2A60]
                                                                                    • Neoplasms
                                                                                      • 5P06276BCHET99799Successful Target
                                                                                    • Pain
                                                                                    • Tonus and reflex abnormality
                                                                                    • [ICD-11: MG30-MG3Z]
                                                                                    • [ICD-11: MB47]
                                                                                    • Symptoms, signs or clinical findings, not elsewhere classified
                                                                                    • Symptoms, signs or clinical findings, not elsewhere classified
                                                                                      • 6Q9HCR9PDE11AT99802Literature-reported Target
                                                                                      7P30550GRPRT99816Clinical trial target
                                                                                    • Breast cancer
                                                                                    • Irritable bowel syndrome
                                                                                    • Solid tumour/cancer
                                                                                    • [ICD-11: 2C60-2C6Y]
                                                                                    • [ICD-11: DD91]
                                                                                    • [ICD-11: 2A00-2F9Z]
                                                                                    • Neoplasms
                                                                                    • Diseases of the digestive system
                                                                                    • Neoplasms
                                                                                      • 8Q96BI3APH1AT99840Successful Target
                                                                                    • Desmoid tumour
                                                                                    • [ICD-11: 2F7C]
                                                                                    • Neoplasms
                                                                                      • 9O15393TMPRSS2T99908Target
                                                                                    • COVID-19
                                                                                    • [ICD-11: 1D6Y]
                                                                                    • Certain infectious or parasitic diseases
                                                                                      • 10Q16719KYNUT99912Preclinical target
                                                                                    • Bacterial infection
                                                                                    • Breast cancer
                                                                                    • [ICD-11: 1A00-1C4Z]
                                                                                    • [ICD-11: 2C60-2C6Y]
                                                                                    • Certain infectious or parasitic diseases
                                                                                    • Neoplasms
                                                                                      • 11Q9NZQ7CD274T99948Successful Target
                                                                                    • Neuroendocrine carcinoma
                                                                                    • Non-small-cell lung cancer
                                                                                    • Solid tumour/cancer
                                                                                    • Ureteral cancer
                                                                                    • [ICD-11: 2C34]
                                                                                    • [ICD-11: 2C25]
                                                                                    • [ICD-11: 2A00-2F9Z]
                                                                                    • [ICD-11: 2C92]
                                                                                    • Neoplasms
                                                                                    • Neoplasms
                                                                                    • Neoplasms
                                                                                    • Neoplasms
                                                                                      • 12P43119PTGIRT99954Successful Target
                                                                                    • Abortion
                                                                                    • Coronary atherosclerosis
                                                                                    • Pulmonary hypertension
                                                                                    • [ICD-11: JA00]
                                                                                    • [ICD-11: BA52]
                                                                                    • [ICD-11: BB01]
                                                                                    • Pregnancy, childbirth or the puerperium
                                                                                    • Diseases of the circulatory system
                                                                                    • Diseases of the circulatory system
                                                                                      • 13P49674CSNK1ET99989Successful Target
                                                                                    • Follicular lymphoma
                                                                                    • Mature B-cell lymphoma
                                                                                    • [ICD-11: 2A80]
                                                                                    • [ICD-11: 2A85]
                                                                                    • Neoplasms
                                                                                    • Neoplasms
                                                                                      • 14P51813BMXT99990Patented-recorded Target