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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q9UBF8	PI4KB	T12541	Clinical trial target	Chronic obstructive pulmonary disease Zoonotic viral disease	[ICD-11: CA22] ICD-11: 1D6Y	Diseases of the respiratory system Certain infectious or parasitic diseases
2	P55072	VCP	T12646	Clinical trial target	Acute myeloid leukaemia Multiple myeloma Myelodysplastic syndrome Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2A83] [ICD-11: 2A37] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms
3	Q16548	BCL2A1	T12797	Patented-recorded Target
4	P17612	PRKACA	T12808	Successful Target	Muscular atrophy	[ICD-11: 8B61]	Diseases of the nervous system
5	P11142	HSPA8	T12817	Literature-reported Target
6	Q86X55	CARM1	T12837	Literature-reported Target
7	P63316	TNNC1	T12966	Successful Target	Acquired cutaneous blood vessel malformation Heart failure	[ICD-11: EF20] [ICD-11: BD10-BD1Z]	Diseases of the skin Diseases of the circulatory system
8	Q06124	PTPN11	T13057	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
9	P48729	CSNK1A1	T13075	Clinical trial target	Malignant haematopoietic neoplasm Solid tumour/cancer	[ICD-11: 2B33] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
10	P49356	FNTB	T13127	Successful Target	Premature ageing appearance	[ICD-11: LD2B]	Developmental anomalies
11	Q9NZJ5	EIF2AK3	T13176	Clinical trial target	Breast cancer	[ICD-11: 2C60-2C6Y]	Neoplasms
12	P00915	CA1	T13201	Successful Target	Glaucoma Seborrhoeic dermatitis	[ICD-11: 9C61] [ICD-11: EA81]	Diseases of the visual system Diseases of the skin
13	P51649	ALDH5A1	T13259	Successful Target	Diagnostic imaging Nutritional deficiency	[ICD-11: N.A.] [ICD-11: 5B50-5B71]	N.A Endocrine, nutritional or metabolic diseases
14	P11511	CYP19A1	T13260	Successful Target	Breast cancer Cushing syndrome	[ICD-11: 2C60-2C6Y] [ICD-11: 5A70]	Neoplasms Endocrine, nutritional or metabolic diseases
15	P27695	APEX1	T13348	Clinical trial target	Retinopathy Solid tumour/cancer	[ICD-11: 9B71] [ICD-11: 2A00-2F9Z]	Diseases of the visual system Neoplasms
16	O43603	GALR2	T13453	Literature-reported Target
17	P43657	LPAR6	T13484	Literature-reported Target
18	Q99808	SLC29A1	T13491	Successful Target	Angina pectoris	[ICD-11: BA40]	Diseases of the circulatory system
19	Q13418	ILK	T13616	Patented-recorded Target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
20	P32745	SSTR3	T13644	Successful Target	Cushing syndrome	[ICD-11: 5A70]	Endocrine, nutritional or metabolic diseases
21	P55055	NR1H2	T13714	Clinical trial target	Atopic eczema	[ICD-11: EA80]	Diseases of the skin
22	P19793	RXRA	T13726	Successful Target	Kaposi sarcoma Mycosis fungoides	[ICD-11: 2B57] [ICD-11: 2B01]	Neoplasms Neoplasms
23	P21453	S1PR1	T13852	Successful Target	Multiple sclerosis Ulcerative colitis	[ICD-11: 8A40] [ICD-11: DD71]	Diseases of the nervous system Diseases of the digestive system
24	Q8IU80	TMPRSS6	T13863	Literature-reported Target
25	O00482	NR5A2	T13902	Literature-reported Target