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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q6DJV7	ICH3	T89565	Patented-recorded Target
2	P14902	IDO1	T89697	Successful Target	Depression	[ICD-11: 6A70-6A7Z]	Mental, behavioural or neurodevelopmental disorders
3	Q15466	NR0B2	T89859	Literature-reported Target
4	P13500	CCL2	T89988	Clinical trial target	Chronic kidney disease Chronic obstructive pulmonary disease Chronic pain Human immunodeficiency virus disease Melanoma Metastatic tumour Multiple sclerosis Pancreatic cancer Rheumatoid arthritis Solid tumour/cancer	[ICD-11: GB61] [ICD-11: CA22] [ICD-11: MG30] [ICD-11: 1C60-1C62] [ICD-11: 2C30] [ICD-11: 2D50-2E2Z] [ICD-11: 8A40] [ICD-11: 2C10] [ICD-11: FA20] [ICD-11: 2A00-2F9Z]	Diseases of the genitourinary system Diseases of the respiratory system Symptoms, signs or clinical findings, not elsewhere classified Certain infectious or parasitic diseases Neoplasms Neoplasms Diseases of the nervous system Neoplasms Diseases of the musculoskeletal system or connective tissue Neoplasms
5	P27448	MARK3	T90553	Clinical trial target	Peritoneal cancer Solid tumour/cancer	[ICD-11: 2C51] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
6	P28476	GABRR2	T90682	Literature-reported Target
7	Q15077	P2RY6	T90782	Clinical trial target	Alzheimer disease	[ICD-11: 8A20]	Diseases of the nervous system
8	Q9Y5X5	NPFFR2	T90818	Literature-reported Target
9	Q9NSY1	BMP2K	T90961	Literature-reported Target
10	Q58F21	BRDT	T90985	Clinical trial target	Testicular cancer	[ICD-11: 2C80]	Neoplasms
11	Q9UHI8	ADAMTS1	T90987	Literature-reported Target
12	P22455	FGFR4	T90989	Clinical trial target	Liver cancer	[ICD-11: 2C12]	Neoplasms
13	Q9UP65	PLA2G4C	T91113	Literature-reported Target
14	P46059	SLC15A1	T91180	Literature-reported Target
15	Q9UEE5	STK17A	T91323	Literature-reported Target
16	P22607	FGFR3	T91331	Successful Target	Coronary atherosclerosis Liver cancer Myocardial infarction	[ICD-11: BA52] [ICD-11: 2C12] [ICD-11: BA41-BA43]	Diseases of the circulatory system Neoplasms Diseases of the circulatory system
17	O14578	CIT	T91397	Literature-reported Target
18	Q09428	ABCC8	T91480	Successful Target	Acute diabete complication Type 2 diabetes mellitus	[ICD-11: 5A2Y] [ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases
19	Q13470	TNK1	T91598	Literature-reported Target
20	P55263	ADK	T91661	Clinical trial target	Epilepsy/seizure	[ICD-11: 8A61-8A6Z]	Diseases of the nervous system
21	Q96KP8	FN1	T91696	Clinical trial target	Vitreous body disorder	[ICD-11: 9B8Z]	Diseases of the visual system
22	Q9NXA8	SIRT5	T91940	Literature-reported Target
23	Q9NTG7	SIRT3	T91959	Literature-reported Target
24	Q15303	ERBB4	T92057	Successful Target	Lung cancer	[ICD-11: 2C25]	Neoplasms
25	P30542	ADORA1	T92072	Successful Target	Orthostatic hypotension	[ICD-11: BA21]	Diseases of the circulatory system