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List of therapeutic targets associated diseases

Showing 1125 to 1150 of 1414 | First « Prev 44 45 46 47 48 Next » Last

Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P13631	RARG	T82146	Successful Target	Acne vulgaris Acute myeloid leukaemia Kaposi sarcoma Muscle calcification/ossification Psoriasis	[ICD-11: ED80] [ICD-11: 2A60] [ICD-11: 2B57] [ICD-11: FB31] [ICD-11: EA90]	Diseases of the skin Neoplasms Neoplasms Diseases of the musculoskeletal system or connective tissue Diseases of the skin
2	Q96RR4	CAMKK2	T82262	Patented-recorded Target
3	P14207	FOLR2	T82297	Literature-reported Target
4	P30530	AXL	T82383	Successful Target	Acute myeloid leukaemia	[ICD-11: 2A60]	Neoplasms
5	Q9P0J0	NDUFA13	T82391	Clinical trial target	Cardiomyopathy	[ICD-11: BC43]	Diseases of the circulatory system
6	P78536	ADAM17	T82393	Clinical trial target	Breast cancer Rheumatoid arthritis	[ICD-11: 2C60-2C6Y] [ICD-11: FA20]	Neoplasms Diseases of the musculoskeletal system or connective tissue
7	Q6PL18	ATAD2	T82467	Literature-reported Target
8	P17787	CHRNB2	T82543	Clinical trial target	Nicotine use disorder	[ICD-11: 6C4A]	Mental, behavioural or neurodevelopmental disorders
9	P78329	CYP4F2	T82604	Literature-reported Target
10	Q14643	ITPR1	T82624	Successful Target	Hypertension	[ICD-11: BA00-BA04]	Diseases of the circulatory system
11	Q9UKH1	PRMT5	T82665	Clinical trial target	Brain cancer Breast cancer Malignant haematopoietic neoplasm Myelodysplastic syndrome Solid tumour/cancer	[ICD-11: 2A00] [ICD-11: 2C60-2C6Y] [ICD-11: 2B33] [ICD-11: 2A37] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms
12	Q8N5Z0	AADAT	T82668	Preclinical target	Mild neurocognitive disorder Schizophrenia	[ICD-11: 6D71] [ICD-11: 6A20]	Mental, behavioural or neurodevelopmental disorders Mental, behavioural or neurodevelopmental disorders
13	O75469	NR1I2	T82702	Literature-reported Target
14	Q9Y463	DYRK1B	T82720	Patented-recorded Target
15	P03952	KLKB1	T82739	Successful Target	Innate/adaptive immunodeficiency Retinal vascular occlusion	[ICD-11: 4A00] [ICD-11: 9B74]	Diseases of the immune system Diseases of the visual system
16	P78368	CSNK1G2	T82773	Literature-reported Target
17	P35222	CTNNB1	T82795	Successful Target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
18	Q15678	PTPN14	T82848	Literature-reported Target
19	P42684	ABL2	T83009	Literature-reported Target
20	P27338	MAOB	T83011	Successful Target	Dementia Depression Hypertension Malaria Migraine Parkinsonism	[ICD-11: 6D80-6D8Z] [ICD-11: 6A70-6A7Z] [ICD-11: BA00-BA04] [ICD-11: 1F40-1F45] [ICD-11: 8A80] [ICD-11: 8A00]	Mental, behavioural or neurodevelopmental disorders Mental, behavioural or neurodevelopmental disorders Diseases of the circulatory system Certain infectious or parasitic diseases Diseases of the nervous system Diseases of the nervous system
21	O95271	TNKS	T83059	Clinical trial target	Brain cancer Breast cancer Ovarian cancer Solid tumour/cancer	[ICD-11: 2A00] [ICD-11: 2C60-2C6Y] [ICD-11: 2C73] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms
22	Q9GZV3	SLC5A7	T83143	Literature-reported Target
23	P19838	NFKB1	T83145	Successful Target	Irritable bowel syndrome Rheumatoid arthritis	[ICD-11: DD91] [ICD-11: FA20]	Diseases of the digestive system Diseases of the musculoskeletal system or connective tissue
24	P41743	PRKCI	T83174	Literature-reported Target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
25	Q8NER1	TRPV1	T83193	Successful Target	General pain disorder	[ICD-11: 8E43]	Diseases of the nervous system