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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q9NY46	SCN3A	T76937	Successful Target	Angina pectoris	[ICD-11: BA40]	Diseases of the circulatory system
2	Q9C098	DCLK3	T77061	Literature-reported Target
3	P03897	MT-ND3	T77195	Successful Target	Parkinsonism	[ICD-11: 8A00]	Diseases of the nervous system
4	Q9UBX1	CTSF	T77236	Patented-recorded Target	Bone cancer Chronic obstructive pulmonary disease Chronic pain Digestive system disease Hepatic fibrosis/cirrhosis Multiple sclerosis Psoriasis	[ICD-11: 2B5Z] [ICD-11: CA22] [ICD-11: MG30] [ICD-11: DE2Z] [ICD-11: DB93] [ICD-11: 8A40] [ICD-11: EA90]	Neoplasms Diseases of the respiratory system Symptoms, signs or clinical findings, not elsewhere classified Diseases of the digestive system Diseases of the digestive system Diseases of the nervous system Diseases of the skin
5	P28062	PSMB8	T77350	Clinical trial target	Multiple myeloma	[ICD-11: 2A83]	Neoplasms
6	P29274	ADORA2A	T77365	Successful Target	Orthostatic hypotension Parkinsonism Radionuclide imaging	[ICD-11: BA21] [ICD-11: 8A00] [ICD-11: N.A.]	Diseases of the circulatory system Diseases of the nervous system N.A
7	P61964	WDR5	T77393	Literature-reported Target
8	O00408	PDE2A	T77400	Clinical trial target	Inborn purine/pyrimidine/nucleotide metabolism error Indeterminate colitis Irritable bowel syndrome Mood disorder	[ICD-11: 5C55] [ICD-11: DD72] [ICD-11: DD91] [ICD-11: 6A60-6E23]	Endocrine, nutritional or metabolic diseases Diseases of the digestive system Diseases of the digestive system Mental, behavioural or neurodevelopmental disorders
9	P12644	BMP4	T77410	Literature-reported Target
10	Q08881	ITK	T77537	Literature-reported Target
11	P19801	AOC1	T77546	Literature-reported Target
12	O00222	GRM8	T77548	Literature-reported Target
13	P11021	HSPA5	T77594	Clinical trial target	Melanoma Solid tumour/cancer	[ICD-11: 2C30] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
14	Q01064	PDE1B	T77613	Patented-recorded Target	Mild neurocognitive disorder	[ICD-11: 6D71]	Mental, behavioural or neurodevelopmental disorders
15	O00220	TNFRSF10A	T77645	Clinical trial target	Lung cancer	[ICD-11: 2C25]	Neoplasms
16	P34981	TRHR	T77796	Successful Target	Central nervous system disease	[ICD-11: 8A04-8D87]	Diseases of the nervous system
17	P35367	HRH1	T77913	Successful Target	Allergic/hypersensitivity disorder Anxiety disorder Breathing abnormality Conjunctiva disorder Cough Depression Episodic vestibular syndrome Headache Insomnia Morning sickness disorder Nasopharyngitis Nausea/vomiting Parkinsonism Pruritus Rheumatoid arthritis Sleep-wake disorder Vasomotor/allergic rhinitis	[ICD-11: 4A80-4A8Z] [ICD-11: 6B00-6B0Z] [ICD-11: MD11] [ICD-11: 9A60] [ICD-11: MD12] [ICD-11: 6A70-6A7Z] [ICD-11: AB31] [ICD-11: 8A80-8A84] [ICD-11: 7A00-7A0Z] [ICD-11: SC00] [ICD-11: CA00] [ICD-11: MD90] [ICD-11: 8A00] [ICD-11: EC90] [ICD-11: FA20] [ICD-11: 7A00-7B2Z] [ICD-11: CA08]	Diseases of the immune system Mental, behavioural or neurodevelopmental disorders Symptoms, signs or clinical findings, not elsewhere classified Diseases of the visual system Symptoms, signs or clinical findings, not elsewhere classified Mental, behavioural or neurodevelopmental disorders Diseases of the ear or mastoid process Diseases of the nervous system Sleep-wake disorders Supplementary Chapter Traditional Medicine Conditions Diseases of the respiratory system Symptoms, signs or clinical findings, not elsewhere classified Diseases of the nervous system Diseases of the skin Diseases of the musculoskeletal system or connective tissue Sleep-wake disorders Diseases of the respiratory system
18	O75365	PTP4A3	T78019	Literature-reported Target
19	Q86VL8	SLC47A2	T78127	Literature-reported Target
20	P00491	PNP	T78198	Clinical trial target	Diabetes mellitus Gout Malignant haematopoietic neoplasm Mycosis fungoides Psoriasis	[ICD-11: 5A10] [ICD-11: FA25] [ICD-11: 2B33] [ICD-11: 2B01] [ICD-11: EA90]	Endocrine, nutritional or metabolic diseases Diseases of the musculoskeletal system or connective tissue Neoplasms Neoplasms Diseases of the skin
21	O94759	TRPM2	T78205	Literature-reported Target
22	Q02083	NAAA	T78326	Literature-reported Target
23	Q15717	ELAVL1	T78349	Literature-reported Target
24	P24557	TBXAS1	T78356	Clinical trial target	Angina pectoris	[ICD-11: BA40]	Diseases of the circulatory system
25	O15111	CHUK	T78429	Clinical trial target	Mature B-cell lymphoma	[ICD-11: 2A85]	Neoplasms