CDMMM (Home)

Browse by therapeutic targets associated diseases

List of therapeutic targets associated diseases

Showing 1025 to 1050 of 1414 | First « Prev 40 41 42 43 44 Next » Last

Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P42345	MTOR	T75243	Successful Target	Arteries/arterioles disorder Chronic myelomonocytic leukaemia Multiple myeloma Renal cell carcinoma Solid tumour/cancer Transplant rejection	[ICD-11: BD52] [ICD-11: 2A40] [ICD-11: 2A83] [ICD-11: 2C90] [ICD-11: 2A00-2F9Z] [ICD-11: NE84]	Diseases of the circulatory system Neoplasms Neoplasms Neoplasms Neoplasms Injury, poisoning or certain other consequences of external causes
2	Q9NPI8	FANCF	T75419	Literature-reported Target
3	P30536	TSPO	T75440	Successful Target	Anxiety disorder Epilepsy/seizure Insomnia Intentional self-harm Mood/affect symptom Tonus and reflex abnormality	[ICD-11: 6B00-6B0Z] [ICD-11: 8A61-8A6Z] [ICD-11: 7A00-7A0Z] [ICD-11: PC91] [ICD-11: MB24] [ICD-11: MB47]	Mental, behavioural or neurodevelopmental disorders Diseases of the nervous system Sleep-wake disorders External causes of morbidity or mortality Symptoms, signs or clinical findings, not elsewhere classified Symptoms, signs or clinical findings, not elsewhere classified
4	P16083	NQO2	T75498	Successful Target	Insomnia	[ICD-11: 7A00-7A0Z]	Sleep-wake disorders
5	P50579	METAP2	T75596	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
6	Q9HC29	NOD2	T75643	Clinical trial target	Diabetes mellitus Hepatitis virus infection	[ICD-11: 5A10] [ICD-11: 1E50-1E51]	Endocrine, nutritional or metabolic diseases Certain infectious or parasitic diseases
7	P98073	TMPRSS15	T75772	Patented-recorded Target
8	P43088	PTGFR	T75797	Successful Target	Abortion Coronary atherosclerosis Glaucoma	[ICD-11: JA00] [ICD-11: BA52] [ICD-11: 9C61]	Pregnancy, childbirth or the puerperium Diseases of the circulatory system Diseases of the visual system
9	Q92523	CPT1B	T75888	Successful Target	Angina pectoris Mild neurocognitive disorder Nutritional deficiency	[ICD-11: BA40] [ICD-11: 6D71] [ICD-11: 5B50-5B71]	Diseases of the circulatory system Mental, behavioural or neurodevelopmental disorders Endocrine, nutritional or metabolic diseases
10	Q12882	DPYD	T75890	Successful Target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
11	Q9UCV4	C1S	T76024	Successful Target	Haemolytic anemia Innate/adaptive immunodeficiency	[ICD-11: 3A20-3A2Z] [ICD-11: 4A00]	Diseases of the blood or blood-forming organs Diseases of the immune system
12	P62942	FKBP1A	T76059	Successful Target	Parkinsonism Pruritus Transplant rejection	[ICD-11: 8A00] [ICD-11: EC90] [ICD-11: NE84]	Diseases of the nervous system Diseases of the skin Injury, poisoning or certain other consequences of external causes
13	P21731	TBXA2R	T76198	Successful Target	Coronary atherosclerosis Diabetic foot ulcer Myocardial infarction Sexual dysfunction	[ICD-11: BA52] [ICD-11: BD54] [ICD-11: BA41-BA43] [ICD-11: HA00-HA01]	Diseases of the circulatory system Diseases of the circulatory system Diseases of the circulatory system Conditions related to sexual health
14	P00439	PAH	T76213	Successful Target	Metabolism inborn error	[ICD-11: 5C50]	Endocrine, nutritional or metabolic diseases
15	P23141	CES1	T76369	Successful Target	Peroxisomal disease Synthesis disorder	[ICD-11: 5C57] [ICD-11: 5C52-5C59]	Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases
16	P53609	PGGT1B	T76396	Clinical trial target	Lymphoma	[ICD-11: 2A80-2A86]	Neoplasms
17	Q13224	GRIN2B	T76414	Successful Target	Alpha-1-antitrypsin deficiency	[ICD-11: 5C5A]	Endocrine, nutritional or metabolic diseases
18	P52209	PGD	T76497	Successful Target	Pituitary gland disorder	[ICD-11: 5A60-5A61]	Endocrine, nutritional or metabolic diseases
19	Q9Y2U5	MAP3K2	T76508	Clinical trial target
20	P21554	CNR1	T76685	Successful Target	Anorexia nervosa Insomnia Obesity	[ICD-11: 6B80] [ICD-11: 7A00-7A0Z] [ICD-11: 5B80-5B81]	Mental, behavioural or neurodevelopmental disorders Sleep-wake disorders Endocrine, nutritional or metabolic diseases
21	O60678	PRMT3	T76723	Literature-reported Target
22	P41968	MC3R	T76846	Literature-reported Target	Obesity Sexual dysfunction Type 2 diabetes mellitus	[ICD-11: 5B80-5B81] [ICD-11: HA00-HA01] [ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases Conditions related to sexual health Endocrine, nutritional or metabolic diseases
23	P21964	COMT	T76904	Successful Target	Parkinsonism	[ICD-11: 8A00]	Diseases of the nervous system
24	P49840	GSK3A	T76910	Successful Target	Epilepsy/seizure	[ICD-11: 8A61-8A6Z]	Diseases of the nervous system
25	P22001	KCNA3	T76914	Clinical trial target	Idiopathic inflammatory myopathy Psoriasis Psoriatic arthritis	[ICD-11: 4A41] [ICD-11: EA90] [ICD-11: FA21]	Diseases of the immune system Diseases of the skin Diseases of the musculoskeletal system or connective tissue