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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P31213	SRD5A2	T71390	Successful Target	Prostate hyperplasia	[ICD-11: GA90]	Diseases of the genitourinary system
2	Q92820	GGH	T71646	Literature-reported Target
3	Q16637	SMN2	T71907	Successful Target	Muscular atrophy	[ICD-11: 8B61]	Diseases of the nervous system
4	Q9Y2K7	KDM2A	T71949	Literature-reported Target
5	P17931	LGALS3	T72038	Clinical trial target	Hypertension Idiopathic interstitial pneumonitis Melanoma Non-alcoholic fatty liver disease Psoriasis	[ICD-11: BA00-BA04] [ICD-11: CB03] [ICD-11: 2C30] [ICD-11: DB92] [ICD-11: EA90]	Diseases of the circulatory system Diseases of the respiratory system Neoplasms Diseases of the digestive system Diseases of the skin
6	P22102	GART	T72042	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
7	P08235	NR3C2	T72168	Successful Target	Adrenocortical insufficiency Chronic kidney disease Contraceptive management Heart failure Hypertension Hypo-osmolality/hyponatraemia	[ICD-11: 5A74] [ICD-11: GB61] [ICD-11: QA21] [ICD-11: BD10-BD1Z] [ICD-11: BA00-BA04] [ICD-11: 5C72]	Endocrine, nutritional or metabolic diseases Diseases of the genitourinary system Factors influencing health status or contact with health services Diseases of the circulatory system Diseases of the circulatory system Endocrine, nutritional or metabolic diseases
8	P55210	CASP7	T72252	Clinical trial target	Cystic fibrosis	[ICD-11: CA25]	Diseases of the respiratory system
9	Q14330	GPR18	T72267	Literature-reported Target
10	P68104	EEF1A1	T72269	Literature-reported Target	Melanoma	[ICD-11: 2C30]	Neoplasms
11	O95931	CBX7	T72319	Literature-reported Target
12	P32245	MC4R	T72458	Successful Target	Hypoactive sexual desire dysfunction Large intestine motility disorder Obesity	[ICD-11: HA00] [ICD-11: DB32] [ICD-11: 5B80-5B81]	Conditions related to sexual health Diseases of the digestive system Endocrine, nutritional or metabolic diseases
13	P30281	CCND3	T72507	Literature-reported Target
14	Q9UKE5	TNIK	T72534	Literature-reported Target
15	Q14957	GRIN2C	T72595	Literature-reported Target	Neurodegenerative disorder	[ICD-11: 8A20-8A23]	Diseases of the nervous system
16	P13726	F3	T72702	Successful Target	Cervical cancer	[ICD-11: 2C77]	Neoplasms
17	O15197	EPHB6	T72732	Literature-reported Target
18	P16581	SELE	T72835	Clinical trial target	Acute myeloid leukaemia Asthma Atopic eczema Chronic obstructive pulmonary disease Circulatory system disease Hypertension Psoriasis	[ICD-11: 2A60] [ICD-11: CA23] [ICD-11: EA80] [ICD-11: CA22] [ICD-11: BE2Z] [ICD-11: BA00-BA04] [ICD-11: EA90]	Neoplasms Diseases of the respiratory system Diseases of the skin Diseases of the respiratory system Diseases of the circulatory system Diseases of the circulatory system Diseases of the skin
19	P11474	ESRRA	T72841	Successful Target	Rheumatoid arthritis	[ICD-11: FA20]	Diseases of the musculoskeletal system or connective tissue
20	Q9NZ08	ERAP1	T72849	Literature-reported Target
21	Q16873	LTC4S	T72881	Patented-recorded Target
22	P16278	GLB1	T73134	Clinical trial target	Lysosomal disease	[ICD-11: 5C56]	Endocrine, nutritional or metabolic diseases
23	P24347	MMP11	T73180	Literature-reported Target
24	Q8WTS6	SETD7	T73184	Literature-reported Target	Breast cancer	[ICD-11: 2C60-2C6Y]	Neoplasms
25	P05981	HPN	T73471	Patented-recorded Target