List of therapeutic targets associated diseases



                                                                                                                                                        Sr. No. Uniprot ID Gene name TTD ID Target type Disease name ICD-11 Disease class
                                                                                                                                                        1P23946CMA1T05114Clinical trial target
                                                                                                                                                      • Atopic eczema
                                                                                                                                                      • Chronic obstructive pulmonary disease
                                                                                                                                                      • Gram-positive bacterial infection
                                                                                                                                                      • Heart failure
                                                                                                                                                      • Left ventricular failure
                                                                                                                                                      • Myocardial infarction
                                                                                                                                                      • [ICD-11: EA80]
                                                                                                                                                      • [ICD-11: CA22]
                                                                                                                                                      • [ICD-11: 1B74-1F40]
                                                                                                                                                      • [ICD-11: BD10-BD1Z]
                                                                                                                                                      • [ICD-11: BD11]
                                                                                                                                                      • [ICD-11: BA41-BA43]
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 2P21980TGM2T05387Clinical trial target
                                                                                                                                                      • Coeliac disease
                                                                                                                                                      • Non-alcoholic fatty liver disease
                                                                                                                                                      • [ICD-11: DA95]
                                                                                                                                                      • [ICD-11: DB92]
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 3P08473MMET05409Clinical trial target
                                                                                                                                                      • Heart failure
                                                                                                                                                      • [ICD-11: BD10-BD1Z]
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 4P32239CCKBRT05849Successful Target
                                                                                                                                                      • Diagnostic imaging
                                                                                                                                                      • Pancreatic internal secretion disorder
                                                                                                                                                      • [ICD-11: N.A.]
                                                                                                                                                      • [ICD-11: 5A4Y]
                                                                                                                                                      • N.A
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 5P45379TNNT2T05887Literature-reported Target
                                                                                                                                                        6O60658PDE8AT05904Patented-recorded Target
                                                                                                                                                      • Itching
                                                                                                                                                      • Postoperative inflammation
                                                                                                                                                      • [ICD-11: 1F28-1G07]
                                                                                                                                                      • [ICD-11: 1A00-CA43]
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Postoperative inflammation
                                                                                                                                                      • 7Q13233MAP3K1T06031Clinical trial target
                                                                                                                                                        8P29474NOS3T06046Clinical trial target
                                                                                                                                                      • Myocardial infarction
                                                                                                                                                      • [ICD-11: BA41-BA43]
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 9O75116ROCK2T06093Successful Target
                                                                                                                                                      • Graft-versus-host disease
                                                                                                                                                      • [ICD-11: 4B24]
                                                                                                                                                      • Diseases of the immune system
                                                                                                                                                      • 10P41587VIPR2T06182Clinical trial target
                                                                                                                                                      • Cardiomyopathy
                                                                                                                                                      • Chronic obstructive pulmonary disease
                                                                                                                                                      • Heart failure
                                                                                                                                                      • Hypertension
                                                                                                                                                      • Muscular dystrophy
                                                                                                                                                      • Pulmonary hypertension
                                                                                                                                                      • [ICD-11: BC43]
                                                                                                                                                      • [ICD-11: CA22]
                                                                                                                                                      • [ICD-11: BD10-BD1Z]
                                                                                                                                                      • [ICD-11: BA00-BA04]
                                                                                                                                                      • [ICD-11: 8C70]
                                                                                                                                                      • [ICD-11: BB01]
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 11P09874PARP1T06273Successful Target
                                                                                                                                                      • Acquired cutaneous blood vessel malformation
                                                                                                                                                      • Fallopian tube cancer
                                                                                                                                                      • Ovarian cancer
                                                                                                                                                      • Peritoneal cancer
                                                                                                                                                      • [ICD-11: EF20]
                                                                                                                                                      • [ICD-11: 2C74]
                                                                                                                                                      • [ICD-11: 2C73]
                                                                                                                                                      • [ICD-11: 2C51]
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 12P11509CYP2A6T06455Successful Target
                                                                                                                                                      • Mycosis fungoides
                                                                                                                                                      • Psoriasis
                                                                                                                                                      • [ICD-11: 2B01]
                                                                                                                                                      • [ICD-11: EA90]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • 13P23280CA6T06569Successful Target
                                                                                                                                                      • Bacterial infection
                                                                                                                                                      • Seborrhoeic dermatitis
                                                                                                                                                      • [ICD-11: 1A00-1C4Z]
                                                                                                                                                      • [ICD-11: EA81]
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • 14P28065PSMB9T06792Patented-recorded Target
                                                                                                                                                        15Q9UBU3GHRLT06850Clinical trial target
                                                                                                                                                      • Diabetes mellitus
                                                                                                                                                      • [ICD-11: 5A10]
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 16P51679CCR4T06955Successful Target
                                                                                                                                                      • Mycosis fungoides
                                                                                                                                                      • Sezary syndrome
                                                                                                                                                      • [ICD-11: 2B01]
                                                                                                                                                      • [ICD-11: 2B02]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 17P06746POLBT06958Clinical trial target
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 18Q14289PTK2BT07087Literature-reported Target
                                                                                                                                                        19P32754HPDT07137Successful Target
                                                                                                                                                      • Metabolism inborn error
                                                                                                                                                      • [ICD-11: 5C50]
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 20P04629NTRK1T07173Successful Target
                                                                                                                                                      • Non-small-cell lung cancer
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 21Q12851MAP4K2T07191Patented-recorded Target
                                                                                                                                                      • Breast cancer
                                                                                                                                                      • [ICD-11: 2C60-2C6Y]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 22P15090FABP4T07217Patented-recorded Target
                                                                                                                                                        23Q9P1W9PIM2T07279Clinical trial target
                                                                                                                                                      • Multiple myeloma
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2A83]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 24P35916FLT4T07303Successful Target
                                                                                                                                                      • Renal cell carcinoma
                                                                                                                                                      • [ICD-11: 2C90]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 25Q15109AGERT07400Clinical trial target
                                                                                                                                                      • Alzheimer disease
                                                                                                                                                      • Chronic kidney disease
                                                                                                                                                      • Dementia
                                                                                                                                                      • Hypotension
                                                                                                                                                      • [ICD-11: 8A20]
                                                                                                                                                      • [ICD-11: GB61]
                                                                                                                                                      • [ICD-11: 6D80-6D8Z]
                                                                                                                                                      • [ICD-11: BA20-BA21]
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the genitourinary system
                                                                                                                                                      • Mental, behavioural or neurodevelopmental disorders
                                                                                                                                                      • Diseases of the circulatory system