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List of therapeutic targets associated diseases

Showing 25 to 50 of 1414 | « Prev 1 2 3 4 Next » Last

Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q13564	NAE1	T01447	Clinical trial target	Myelodysplastic syndrome	[ICD-11: 2A37]	Neoplasms
2	Q8N183	NDUFAF2	T01453	Target
3	Q9Y6M9	NDUFB9	T01465	Target
4	O95470	SGPL1	T01575	Clinical trial target	Congenital ichthyosis Rheumatoid arthritis	[ICD-11: EC20] [ICD-11: FA20]	Diseases of the skin Diseases of the musculoskeletal system or connective tissue
5	P18825	ADRA2C	T01777	Successful Target	Glaucoma Hypertension Hypotension Obesity Ocular disease Substance abuse	[ICD-11: 9C61] [ICD-11: BA00-BA04] [ICD-11: BA20-BA21] [ICD-11: 5B80-5B81] [ICD-11: N.A.] [ICD-11: 6C40]	Diseases of the visual system Diseases of the circulatory system Diseases of the circulatory system Endocrine, nutritional or metabolic diseases N.A Mental, behavioural or neurodevelopmental disorders
6	P05556	ITGB1	T01851	Clinical trial target	Brain cancer Lung cancer Retinopathy	[ICD-11: 2A00] [ICD-11: 2C25] [ICD-11: 9B71]	Neoplasms Neoplasms Diseases of the visual system
7	P20151	KLK2	T01908	Clinical trial target	Innate/adaptive immunodeficiency	[ICD-11: 4A00]	Diseases of the immune system
8	Q04912	MST1R	T01973	Clinical trial target	Alzheimer disease	[ICD-11: 8A20]	Diseases of the nervous system
9	Q08499	PDE4D	T02001	Successful Target	Tonus and reflex abnormality	[ICD-11: MB47]	Symptoms, signs or clinical findings, not elsewhere classified
10	Q16602	CALCRL	T02226	Target
11	P28340	POLD1	T02258	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
12	Q9BQI3	EIF2AK1	T02439	Literature-reported Target
13	P54762	EPHB1	T02446	Literature-reported Target
14	P03372	ESR1	T02506	Target	COVID-19	[ICD-11: 1D6Y]	Certain infectious or parasitic diseases
15	P35499	SCN4A	T02546	Clinical trial target	Musculoskeletal disorder	[ICD-11: FA00-FC0Z]	Diseases of the musculoskeletal system or connective tissue
16	P35462	DRD3	T02551	Successful Target	Bipolar disorder Parkinsonism	[ICD-11: 6A60] [ICD-11: 8A00]	Mental, behavioural or neurodevelopmental disorders Diseases of the nervous system
17	O14684	PTGES	T02562	Clinical trial target	Alzheimer disease	[ICD-11: 8A20]	Diseases of the nervous system
18	Q9NPD5	SLCO1B3	T02565	Literature-reported Target
19	O15392	BIRC5	T02677	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
20	P35228	NOS2	T02703	Clinical trial target	Chronic kidney disease Osteoarthritis Sepsis Solid tumour/cancer	[ICD-11: GB61] [ICD-11: FA00-FA05] [ICD-11: 1G40-1G41] [ICD-11: 2A00-2F9Z]	Diseases of the genitourinary system Diseases of the musculoskeletal system or connective tissue Certain infectious or parasitic diseases Neoplasms
21	Q14832	GRM3	T02719	Clinical trial target	Schizophrenia	[ICD-11: 6A20]	Mental, behavioural or neurodevelopmental disorders
22	P30989	NTSR1	T02728	Clinical trial target	Indeterminate colitis	[ICD-11: DD72]	Diseases of the digestive system
23	O60706	ABCC9	T02777	Successful Target	Acute diabete complication Angina pectoris Type 2 diabetes mellitus	[ICD-11: 5A2Y] [ICD-11: BA40] [ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases Diseases of the circulatory system Endocrine, nutritional or metabolic diseases
24	Q9Y4D2	DAGLA	T03150	Patented-recorded Target
25	P51812	RPS6KA3	T03279	Patented-recorded Target	Mature B-cell leukaemia	[ICD-11: 2A82]	Neoplasms