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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P02768	ALB	T63068	Successful Target	Aneurysm/dissection Bowel habit change Cholelithiasis Inborn energy metabolism error Irritable bowel syndrome Preprocedural examination Rheumatoid arthritis Schizophrenia Unspecific body region injury	[ICD-11: BD50] [ICD-11: ME05] [ICD-11: DC11] [ICD-11: 5C53] [ICD-11: DD91] [ICD-11: QA0B] [ICD-11: FA20] [ICD-11: 6A20] [ICD-11: ND56]	Diseases of the circulatory system Symptoms, signs or clinical findings, not elsewhere classified Diseases of the digestive system Endocrine, nutritional or metabolic diseases Diseases of the digestive system Factors influencing health status or contact with health services Diseases of the musculoskeletal system or connective tissue Mental, behavioural or neurodevelopmental disorders Injury, poisoning or certain other consequences of external causes
2	Q06609	RAD51	T63083	Clinical trial target	B-cell lymphoma Solid tumour/cancer	[ICD-11: 2A86] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
3	O00754	MAN2B1	T63156	Successful Target	Lysosomal disease	[ICD-11: 5C56]	Endocrine, nutritional or metabolic diseases
4	P51684	CCR6	T63165	Clinical trial target	Indeterminate colitis	[ICD-11: DD72]	Diseases of the digestive system
5	Q9UJM8	HAO1	T63170	Clinical trial target	Inborn carbohydrate metabolism error	[ICD-11: 5C51]	Endocrine, nutritional or metabolic diseases
6	Q9H999	PANK3	T63183	Clinical trial target	Metabolism inborn error	[ICD-11: 5C50]	Endocrine, nutritional or metabolic diseases
7	P22413	ENPP1	T63194	Clinical trial target	Pseudoxanthoma elasticum Vitamin/non-protein cofactor absorption/transport disorder	ICD-11: EC40 ICD-11: 5C63	Diseases of the skin Endocrine, nutritional or metabolic diseases
8	P06865	HEXA	T63196	Clinical trial target	Lysosomal disease	[ICD-11: 5C56]	Endocrine, nutritional or metabolic diseases
9	P07686	HEXB	T63197	Clinical trial target	Lysosomal disease	[ICD-11: 5C56]	Endocrine, nutritional or metabolic diseases
10	Q9NS86	LANCL2	T63207	Clinical trial target	Rheumatoid arthritis Ulcerative colitis	[ICD-11: FA20] [ICD-11: DD71]	Diseases of the musculoskeletal system or connective tissue Diseases of the digestive system
11	P22735	TGM1	T63217	Clinical trial target	Autosomal Recessive Ichthyosis	[ICD-11: EC20]	Diseases of the skin
12	Q07912	TNK2	T63220	Patented-recorded Target
13	P05089	ARG1	T63224	Clinical trial target	Metabolism inborn error	[ICD-11: 5C50]	Endocrine, nutritional or metabolic diseases
14	Q99523	SORT1	T63233	Clinical trial target	Frontotemporal dementia	[ICD-11: 6D83]	Mental, behavioural or neurodevelopmental disorders
15	Q9UMJ8	GBA1	T63243	Clinical trial target	Lysosomal disease	[ICD-11: 5C56]	Endocrine, nutritional or metabolic diseases
16	Q3SYC2	MOGAT2	T63245	Clinical trial target	Obesity	[ICD-11: 5B80-5B81]	Endocrine, nutritional or metabolic diseases
17	Q99572	P2RX7	T63414	Clinical trial target	Joint pain	[ICD-11: ME82]	Symptoms, signs or clinical findings, not elsewhere classified
18	P11413	G6PD	T63484	Successful Target	Chronic obstructive pulmonary disease	[ICD-11: CA22]	Diseases of the respiratory system
19	P00519	ABL1	T63505	Successful Target	Breast cancer Ischemia Mature B-cell lymphoma Nutritional deficiency	[ICD-11: 2C60-2C6Y] [ICD-11: 8B10-8B11] [ICD-11: 2A85] [ICD-11: 5B50-5B71]	Neoplasms Diseases of the nervous system Neoplasms Endocrine, nutritional or metabolic diseases
20	Q13822	ENPP2	T63512	Clinical trial target	Idiopathic interstitial pneumonitis	[ICD-11: CB03]	Diseases of the respiratory system
21	Q08828	ADCY1	T63609	Successful Target	Nutritional deficiency	[ICD-11: 5B50-5B71]	Endocrine, nutritional or metabolic diseases
22	Q9H2K8	TAOK3	T63682	Literature-reported Target
23	P56524	HDAC4	T63816	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
24	P51617	IRAK1	T63846	Patented-recorded Target
25	P17948	FLT1	T63966	Successful Target	Renal cell carcinoma	[ICD-11: 2C90]	Neoplasms