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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P09238	MMP10	T40488	Patented-recorded Target
2	P67775	PPP2CA	T40491	Clinical trial target	Molluscum contagiosum	[ICD-11: 1E76]	Certain infectious or parasitic diseases
3	Q6P1M0	SLC27A4	T40545	Literature-reported Target
4	P30307	CDC25C	T40569	Literature-reported Target
5	P26439	HSD3B2	T40628	Literature-reported Target	Abortion	[ICD-11: JA00]	Pregnancy, childbirth or the puerperium
6	P53350	PLK1	T40694	Clinical trial target	Acute myeloid leukaemia Myelodysplastic syndrome Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2A37] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms
7	Q13126	MTAP	T40787	Literature-reported Target	Multiple sclerosis	[ICD-11: 8A40]	Diseases of the nervous system
8	P05023	ATP1A1	T40800	Successful Target	Cardiac arrhythmia Chronic obstructive pulmonary disease Corneal disease Heart failure Hyperhidrosis Malaria Supraventricular tachyarrhythmia	[ICD-11: BC9Z] [ICD-11: CA22] [ICD-11: 9A76-9A78] [ICD-11: BD10-BD1Z] [ICD-11: EE00] [ICD-11: 1F40-1F45] [ICD-11: BC81]	Diseases of the circulatory system Diseases of the respiratory system Diseases of the visual system Diseases of the circulatory system Diseases of the skin Certain infectious or parasitic diseases Diseases of the circulatory system
9	Q9UGN5	PARP2	T40812	Clinical trial target	Ovarian cancer Solid tumour/cancer	[ICD-11: 2C73] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms
10	P08151	GLI1	T40890	Patented-recorded Target
11	P47989	XDH	T40954	Successful Target	Inborn purine/pyrimidine/nucleotide metabolism error Mineral deficiency	[ICD-11: 5C55] [ICD-11: 5B5K]	Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases
12	P22736	NR4A1	T41119	Literature-reported Target
13	P55201	BRPF1	T41145	Literature-reported Target
14	P16444	DPEP1	T41201	Successful Target	Bacterial infection	[ICD-11: 1A00-1C4Z]	Certain infectious or parasitic diseases
15	Q7RTX1	TAS1R1	T41263	Successful Target	Cholera	[ICD-11: 1A00]	Certain infectious or parasitic diseases
16	P18089	ADRA2B	T41580	Successful Target	Substance abuse	[ICD-11: 6C40]	Mental, behavioural or neurodevelopmental disorders
17	Q9HCP0	CSNK1G1	T41702	Literature-reported Target
18	P48546	GIPR	T41750	Successful Target	Type 2 diabetes mellitus	[ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases
19	Q7Z2W7	TRPM8	T41955	Successful Target	Upper respiratory tract disorder	[ICD-11: CA0Z]	Diseases of the respiratory system
20	P01584	IL1B	T42000	Successful Target	Mineral excesses Monogenic autoinflammatory syndrome Osteoarthritis Rheumatoid arthritis	[ICD-11: 5B91] [ICD-11: 4A60] [ICD-11: FA00-FA05] [ICD-11: FA20]	Endocrine, nutritional or metabolic diseases Diseases of the immune system Diseases of the musculoskeletal system or connective tissue Diseases of the musculoskeletal system or connective tissue
21	O95718	ESRRB	T42025	Literature-reported Target
22	Q15059	BRD3	T42048	Clinical trial target	Acute myeloid leukaemia Prostate cancer	[ICD-11: 2A60] [ICD-11: 2C82]	Neoplasms Neoplasms
23	Q56UN5	MAP3K19	T42157	Patented-recorded Target	Breast cancer	[ICD-11: 2C60-2C6Y]	Neoplasms
24	P53582	METAP1	T42337	Literature-reported Target
25	P42262	GRIA2	T42392	Successful Target	Neuropathy	[ICD-11: 8C0Z]	Diseases of the nervous system