List of therapeutic targets associated diseases



                                                                                                                                                        Sr. No. Uniprot ID Gene name TTD ID Target type Disease name ICD-11 Disease class
                                                                                                                                                        1Q9Y478PRKAB1T38875Clinical trial target
                                                                                                                                                      • Acute diabete complication
                                                                                                                                                      • [ICD-11: 5A2Y]
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 2Q13393PLD1T38996Patented-recorded Target
                                                                                                                                                        3P33316DUTT39054Clinical trial target
                                                                                                                                                      • Lung cancer
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 4Q9P0G3KLK14T39195Patented-recorded Target
                                                                                                                                                        5P04406GAPDHT39321Clinical trial target
                                                                                                                                                      • Muscular atrophy
                                                                                                                                                      • Muscular dystrophy
                                                                                                                                                      • [ICD-11: 8B61]
                                                                                                                                                      • [ICD-11: 8C70]
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • 6Q9HBW0LPAR2T39380Literature-reported Target
                                                                                                                                                        7Q92630DYRK2T39486Patented-recorded Target
                                                                                                                                                        8O43463SUV39H1T39519Literature-reported Target
                                                                                                                                                        9Q96HK3CALMT39610Successful Target
                                                                                                                                                      • Cardiac arrhythmia
                                                                                                                                                      • Malaria
                                                                                                                                                      • Schizophrenia
                                                                                                                                                      • [ICD-11: BC9Z]
                                                                                                                                                      • [ICD-11: 1F40-1F45]
                                                                                                                                                      • [ICD-11: 6A20]
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Mental, behavioural or neurodevelopmental disorders
                                                                                                                                                      • 10Q96FL8SLC47A1T39676Successful Target
                                                                                                                                                      • Type 2 diabetes mellitus
                                                                                                                                                      • [ICD-11: 5A11]
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 11P19835CELT39677Clinical trial target
                                                                                                                                                      • Pancreas disease
                                                                                                                                                      • [ICD-11: DC35-DC3Z]
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 12Q14524SCN5AT39716Successful Target
                                                                                                                                                      • Bacterial infection
                                                                                                                                                      • Cardiac arrhythmia
                                                                                                                                                      • Corneal disease
                                                                                                                                                      • Cough
                                                                                                                                                      • Epilepsy/seizure
                                                                                                                                                      • Migraine
                                                                                                                                                      • Pain
                                                                                                                                                      • Ventricular tachyarrhythmia
                                                                                                                                                      • [ICD-11: 1A00-1C4Z]
                                                                                                                                                      • [ICD-11: BC9Z]
                                                                                                                                                      • [ICD-11: 9A76-9A78]
                                                                                                                                                      • [ICD-11: MD12]
                                                                                                                                                      • [ICD-11: 8A61-8A6Z]
                                                                                                                                                      • [ICD-11: 8A80]
                                                                                                                                                      • [ICD-11: MG30-MG3Z]
                                                                                                                                                      • [ICD-11: BC71]
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • Diseases of the visual system
                                                                                                                                                      • Symptoms, signs or clinical findings, not elsewhere classified
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Symptoms, signs or clinical findings, not elsewhere classified
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 13P38936CAP20T39855Literature-reported Target
                                                                                                                                                        14O15439ABCC4T39919Literature-reported Target
                                                                                                                                                        15P04792HSPB1T39921Clinical trial target
                                                                                                                                                      • Asthma
                                                                                                                                                      • [ICD-11: CA23]
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • 16P14174MIFT39977Clinical trial target
                                                                                                                                                      • Thrombocytopenia
                                                                                                                                                      • [ICD-11: 3B64]
                                                                                                                                                      • Diseases of the blood or blood-forming organs
                                                                                                                                                      • 17Q9H9B1EHMT1T39996Literature-reported Target
                                                                                                                                                      • Breast cancer
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2C60-2C6Y]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 18P06870KLK1T40000Literature-reported Target
                                                                                                                                                        19P04150NR3C1T40016Successful Target
                                                                                                                                                      • Adaptive immunity immunodeficiency
                                                                                                                                                      • Allergic/hypersensitivity disorder
                                                                                                                                                      • Asthma
                                                                                                                                                      • Chronic obstructive pulmonary disease
                                                                                                                                                      • Cushing syndrome
                                                                                                                                                      • Muscular dystrophy
                                                                                                                                                      • Oesophagitis
                                                                                                                                                      • Postoperative inflammation
                                                                                                                                                      • Rheumatoid arthritis
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • Vasomotor/allergic rhinitis
                                                                                                                                                      • [ICD-11: 4A01]
                                                                                                                                                      • [ICD-11: 4A80-4A8Z]
                                                                                                                                                      • [ICD-11: CA23]
                                                                                                                                                      • [ICD-11: CA22]
                                                                                                                                                      • [ICD-11: 5A70]
                                                                                                                                                      • [ICD-11: 8C70]
                                                                                                                                                      • [ICD-11: DA24]
                                                                                                                                                      • [ICD-11: 1A00-CA43]
                                                                                                                                                      • [ICD-11: FA20]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • [ICD-11: CA08]
                                                                                                                                                      • Diseases of the immune system
                                                                                                                                                      • Diseases of the immune system
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • Postoperative inflammation
                                                                                                                                                      • Diseases of the musculoskeletal system or connective tissue
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • 20P45983MAPK8T40097Clinical trial target
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 21P09668CTSHT40103Literature-reported Target
                                                                                                                                                        22P20839IMPDH1T40111Successful Target
                                                                                                                                                      • Breast cancer
                                                                                                                                                      • Hepatitis virus infection
                                                                                                                                                      • Mature B-cell lymphoma
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • Transplant rejection
                                                                                                                                                      • [ICD-11: 2C60-2C6Y]
                                                                                                                                                      • [ICD-11: 1E50-1E51]
                                                                                                                                                      • [ICD-11: 2A85]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • [ICD-11: NE84]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Injury, poisoning or certain other consequences of external causes
                                                                                                                                                      • 23P24723PRKCHT40149Literature-reported Target
                                                                                                                                                      • Human immunodeficiency virus disease
                                                                                                                                                      • [ICD-11: 1C60-1C62]
                                                                                                                                                      • Certain infectious or parasitic diseases
                                                                                                                                                      • 24P05771PRKCBT40276Clinical trial target
                                                                                                                                                      • Diffuse large B-cell lymphoma
                                                                                                                                                      • Lymphoma
                                                                                                                                                      • Malignant haematopoietic neoplasm
                                                                                                                                                      • [ICD-11: 2A81]
                                                                                                                                                      • [ICD-11: 2A80-2A86]
                                                                                                                                                      • [ICD-11: 2B33]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 25P08581METT40474Successful Target
                                                                                                                                                      • Lung cancer
                                                                                                                                                      • Non-small-cell lung cancer
                                                                                                                                                      • Thyroid cancer
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2D10]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms