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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q9ULW8	PADI3	T36612	Literature-reported Target
2	P15086	CPB1	T36725	Patented-recorded Target
3	O15151	MDM4	T36741	Clinical trial target	Acute myeloid leukaemia Malignant haematopoietic neoplasm Myelodysplastic syndrome Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2B33] [ICD-11: 2A37] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms
4	P07288	KLK3	T36935	Clinical trial target	Arteries/arterioles disorder Prostate cancer Prostate hyperplasia	[ICD-11: BD52] [ICD-11: 2C82] [ICD-11: GA90]	Diseases of the circulatory system Neoplasms Diseases of the genitourinary system
5	P37023	ACVRL1	T36959	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
6	P10619	CTSA	T37154	Clinical trial target	Acute diabete complication	[ICD-11: 5A2Y]	Endocrine, nutritional or metabolic diseases
7	Q99417	MYCBP	T37298	Clinical trial target	Liver cancer	[ICD-11: 2C12]	Neoplasms
8	Q96RG2	PASK	T37371	Literature-reported Target
9	Q9GZN0	GPR88	T37505	Literature-reported Target
10	P12259	F5	T37510	Successful Target	Cerebral ischaemia Sepsis	[ICD-11: 8B1Z] [ICD-11: 1G40-1G41]	Diseases of the nervous system Certain infectious or parasitic diseases
11	P20273	CD22	T37539	Successful Target	Lyme borreliosis Malignant haematopoietic neoplasm Mature B-cell leukaemia Mature B-cell lymphoma	[ICD-11: 1C1G] [ICD-11: 2B33] [ICD-11: 2A82] [ICD-11: 2A85]	Certain infectious or parasitic diseases Neoplasms Neoplasms Neoplasms
12	P43166	CA7	T37541	Patented-recorded Target
13	P34972	CNR2	T37693	Successful Target	Attention deficit hyperactivity disorder Insomnia	[ICD-11: 6A05] [ICD-11: 7A00-7A0Z]	Mental, behavioural or neurodevelopmental disorders Sleep-wake disorders
14	P08684	CYP3A4	T37848	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
15	Q13153	PAK1	T37961	Literature-reported Target
16	P48549	KCNJ3	T38012	Literature-reported Target
17	Q9H2K2	TNKS2	T38087	Clinical trial target	Ovarian cancer	[ICD-11: 2C73]	Neoplasms
18	Q8N5S9	CAMKK1	T38134	Literature-reported Target
19	Q4QXX7	MRGPRX2	T38187	Literature-reported Target
20	P48066	SLC6A11	T38200	Clinical trial target	Indeterminate colitis	[ICD-11: DD72]	Diseases of the digestive system
21	Q00975	CACNA1B	T38338	Successful Target	Migraine Non-thrombocytopenic purpura Pain	[ICD-11: 8A80] [ICD-11: 3B60] [ICD-11: MG30-MG3Z]	Diseases of the nervous system Diseases of the blood or blood-forming organs Symptoms, signs or clinical findings, not elsewhere classified
22	P00748	F12	T38509	Clinical trial target	Innate/adaptive immunodeficiency	[ICD-11: 4A00]	Diseases of the immune system
23	P43116	PTGER2	T38529	Successful Target	Abortion Coronary atherosclerosis Diabetic foot ulcer Glaucoma Pulmonary hypertension Sexual dysfunction Transplant rejection	[ICD-11: JA00] [ICD-11: BA52] [ICD-11: BD54] [ICD-11: 9C61] [ICD-11: BB01] [ICD-11: HA00-HA01] [ICD-11: NE84]	Pregnancy, childbirth or the puerperium Diseases of the circulatory system Diseases of the circulatory system Diseases of the visual system Diseases of the circulatory system Conditions related to sexual health Injury, poisoning or certain other consequences of external causes
24	Q92824	PCSK5	T38581	Literature-reported Target
25	Q04756	HGFAC	T38584	Literature-reported Target