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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	Q07075	ENPEP	T31956	Clinical trial target	Hypertension	[ICD-11: BA00-BA04]	Diseases of the circulatory system
2	Q9NRA0	SPHK2	T31989	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
3	Q9ULX7	CA14	T31992	Successful Target	Bacterial infection Inborn metabolism deficiency	[ICD-11: 1A00-1C4Z] [ICD-11: 5C50-5C59]	Certain infectious or parasitic diseases Endocrine, nutritional or metabolic diseases
4	P28223	HTR2A	T32060	Successful Target	Acute diabete complication Anxiety disorder Cerebral ischaemia Mood disorder Parkinsonism Pituitary gland disorder Schizophrenia	[ICD-11: 5A2Y] [ICD-11: 6B00-6B0Z] [ICD-11: 8B1Z] [ICD-11: 6A60-6E23] [ICD-11: 8A00] [ICD-11: 5A60-5A61] [ICD-11: 6A20]	Endocrine, nutritional or metabolic diseases Mental, behavioural or neurodevelopmental disorders Diseases of the nervous system Mental, behavioural or neurodevelopmental disorders Diseases of the nervous system Endocrine, nutritional or metabolic diseases Mental, behavioural or neurodevelopmental disorders
5	P05231	IL6	T32578	Successful Target	Anemia	[ICD-11: 3A00-3A9Z]	Diseases of the blood or blood-forming organs
6	P42681	TXK	T32590	Literature-reported Target
7	Q2M2I8	AAK1	T32764	Clinical trial target	General pain disorder	[ICD-11: 8E43]	Diseases of the nervous system
8	O15120	AGPAT2	T32821	Literature-reported Target
9	Q9GZT9	EGLN1	T32880	Patented-recorded Target
10	Q16850	CYP51A1	T32972	Clinical trial target	Infectious meningitis Nail/perionychium infection Onchocerciasis	[ICD-11: 1D01] [ICD-11: EE12] [ICD-11: 1F6A]	Certain infectious or parasitic diseases Diseases of the skin Certain infectious or parasitic diseases
11	Q99538	LGMN	T32973	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
12	P14920	DAO	T33124	Clinical trial target	Ataxic disorder Schizophrenia	[ICD-11: 8A03] [ICD-11: 6A20]	Diseases of the nervous system Mental, behavioural or neurodevelopmental disorders
13	Q16549	PCSK7	T33211	Literature-reported Target
14	P17936	IGFBP3	T33455	Clinical trial target	Dementia	[ICD-11: 6D80-6D8Z]	Mental, behavioural or neurodevelopmental disorders
15	P08842	STS	T33489	Successful Target	Allergic/hypersensitivity disorder	[ICD-11: 4A80-4A8Z]	Diseases of the immune system
16	Q9NUW8	TDP1	T33492	Patented-recorded Target
17	P42261	GRIA1	T33584	Successful Target	Neuropathy	[ICD-11: 8C0Z]	Diseases of the nervous system
18	Q9UHC9	NPC1L1	T33901	Successful Target	Hyper-lipoproteinaemia	[ICD-11: 5C80]	Endocrine, nutritional or metabolic diseases
19	Q13304	GPR17	T33902	Literature-reported Target
20	Q96JM7	L3MBTL3	T33931	Literature-reported Target
21	P15085	CPA1	T33966	Literature-reported Target
22	P11473	VDR	T34234	Successful Target	Chronic kidney disease Hair/hair growth developmental defect Hyper-parathyroidism Hypo-parathyroidism Mineral deficiency Psoriasis Vitamin deficiency	[ICD-11: GB61] [ICD-11: LC30] [ICD-11: 5A51] [ICD-11: 5A50] [ICD-11: 5B5K] [ICD-11: EA90] [ICD-11: 5B55-5B5F]	Diseases of the genitourinary system Developmental anomalies Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases Endocrine, nutritional or metabolic diseases Diseases of the skin Endocrine, nutritional or metabolic diseases
23	P50336	PPOX	T34239	Successful Target	Epidermal dysplasias	[ICD-11: EK90]	Diseases of the skin
24	P45452	MMP13	T34296	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
25	P36544	CHRNA7	T34429	Successful Target	Corneal disease Schizophrenia	[ICD-11: 9A76-9A78] [ICD-11: 6A20]	Diseases of the visual system Mental, behavioural or neurodevelopmental disorders