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List of therapeutic targets associated diseases

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Sr. No.	Uniprot ID	Gene name	TTD ID	Target type	Disease name	ICD-11	Disease class
1	P29375	KDM5A	T28052	Patented-recorded Target
2	Q9NY47	CACNA2D2	T28132	Literature-reported Target
3	O15552	FFAR2	T28213	Clinical trial target	Abortion Acute diabete complication	[ICD-11: JA00] [ICD-11: 5A2Y]	Pregnancy, childbirth or the puerperium Endocrine, nutritional or metabolic diseases
4	P32238	CCKAR	T28330	Clinical trial target	Influenza Pancreatic malfunction	[ICD-11: 1E30-1E32] [ICD-11: DC30-DC3Z]	Certain infectious or parasitic diseases Diseases of the digestive system
5	P29320	EPHA3	T28413	Clinical trial target	Acute myeloid leukaemia Brain cancer Malignant haematopoietic neoplasm Myelodysplastic syndrome	[ICD-11: 2A60] [ICD-11: 2A00] [ICD-11: 2B33] [ICD-11: 2A37]	Neoplasms Neoplasms Neoplasms Neoplasms
6	P21709	EPHA1	T28418	Literature-reported Target
7	P52732	KIF11	T28484	Clinical trial target	Acute myeloid leukaemia Head and neck cancer Lymphoma Malignant haematopoietic neoplasm Multiple myeloma Ovarian cancer Renal cell carcinoma Solid tumour/cancer	[ICD-11: 2A60] [ICD-11: 2D42] [ICD-11: 2A80-2A86] [ICD-11: 2B33] [ICD-11: 2A83] [ICD-11: 2C73] [ICD-11: 2C90] [ICD-11: 2A00-2F9Z]	Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms Neoplasms
8	P06858	LPL	T28692	Successful Target	Hyper-lipoproteinaemia	[ICD-11: 5C80]	Endocrine, nutritional or metabolic diseases
9	O96017	CHEK2	T28713	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
10	Q9BY41	HDAC8	T28887	Clinical trial target	Solid tumour/cancer	[ICD-11: 2A00-2F9Z]	Neoplasms
11	P11229	CHRM1	T28893	Successful Target	Abdominal pelvic pain Chronic obstructive pulmonary disease Corneal disease Dystonic disorder Functional bladder disorder Gastric ulcer Glaucoma Hyperhidrosis Irritable bowel syndrome Parkinsonism Peptic ulcer Sebaceous gland disorder	[ICD-11: MD81] [ICD-11: CA22] [ICD-11: 9A76-9A78] [ICD-11: 8A02] [ICD-11: GC50] [ICD-11: DA60] [ICD-11: 9C61] [ICD-11: EE00] [ICD-11: DD91] [ICD-11: 8A00] [ICD-11: DA61] [ICD-11: ED91]	Symptoms, signs or clinical findings, not elsewhere classified Diseases of the respiratory system Diseases of the visual system Diseases of the nervous system Diseases of the genitourinary system Diseases of the digestive system Diseases of the visual system Diseases of the skin Diseases of the digestive system Diseases of the nervous system Diseases of the digestive system Diseases of the skin
12	P07332	FES	T29083	Literature-reported Target
13	P40763	STAT3	T29130	Successful Target	Psoriasis	[ICD-11: EA90]	Diseases of the skin
14	Q9Y6K1	DNMT3A	T29355	Patented-recorded Target
15	P35368	ADRA1B	T29500	Successful Target	Attention deficit hyperactivity disorder Hypertension Mental/behavioural/neurodevelopmental disorder Obesity Pain	[ICD-11: 6A05] [ICD-11: BA00-BA04] [ICD-11: 6E20-6E8Z] [ICD-11: 5B80-5B81] [ICD-11: MG30-MG3Z]	Mental, behavioural or neurodevelopmental disorders Diseases of the circulatory system Mental, behavioural or neurodevelopmental disorders Endocrine, nutritional or metabolic diseases Symptoms, signs or clinical findings, not elsewhere classified
16	P10070	GLI2	T29672	Literature-reported Target
17	Q99250	SCN2A	T29678	Literature-reported Target
18	P29371	TACR3	T29683	Successful Target	Menopausal disorder	[ICD-11: GA30]	Diseases of the genitourinary system
19	Q9Y6M4	CSNK1G3	T29728	Literature-reported Target
20	Q9NPH5	NOX4	T29741	Clinical trial target	Fibrosis	[ICD-11: GA14-GC01]	Diseases of the genitourinary system
21	P08648	ITGA5	T29879	Clinical trial target	Retinopathy	[ICD-11: 9B71]	Diseases of the visual system
22	P04183	TK1	T30081	Successful Target	Acute myeloid leukaemia Human immunodeficiency virus disease	[ICD-11: 2A60] [ICD-11: 1C60-1C62]	Neoplasms Certain infectious or parasitic diseases
23	P22303	ACHE	T30082	Successful Target	Alzheimer disease Glaucoma Myasthenia gravis Oesophageal/gastroduodenal disorder Pediculosis Unspecific substance harmful effect	[ICD-11: 8A20] [ICD-11: 9C61] [ICD-11: 8C6Y] [ICD-11: DD90] [ICD-11: 1G00] [ICD-11: NE6Z]	Diseases of the nervous system Diseases of the visual system Diseases of the nervous system Diseases of the digestive system Certain infectious or parasitic diseases Injury, poisoning or certain other consequences of external causes
24	P31639	SLC5A2	T30085	Successful Target	Diabetes mellitus Heart failure Type 2 diabetes mellitus	[ICD-11: 5A10] [ICD-11: BD10-BD1Z] [ICD-11: 5A11]	Endocrine, nutritional or metabolic diseases Diseases of the circulatory system Endocrine, nutritional or metabolic diseases
25	Q16581	C3AR1	T30219	Literature-reported Target