List of therapeutic targets associated diseases



                                                                                                                                                        Sr. No. Uniprot ID Gene name TTD ID Target type Disease name ICD-11 Disease class
                                                                                                                                                        1P14679TYRT97035Successful Target
                                                                                                                                                      • Acquired hypermelanosis
                                                                                                                                                      • Acquired hypomelanotic disorder
                                                                                                                                                      • [ICD-11: ED60]
                                                                                                                                                      • [ICD-11: ED63]
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • Diseases of the skin
                                                                                                                                                      • 2Q04609FOLH1T97071Successful Target
                                                                                                                                                      • Diagnostic imaging
                                                                                                                                                      • Prostate cancer
                                                                                                                                                      • [ICD-11: N.A.]
                                                                                                                                                      • [ICD-11: 2C82]
                                                                                                                                                      • N.A
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 3Q9BUB5MKNK1T97136Clinical trial target
                                                                                                                                                      • Breast cancer
                                                                                                                                                      • Colorectal cancer
                                                                                                                                                      • Liver cancer
                                                                                                                                                      • Lymphoma
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2C60-2C6Y]
                                                                                                                                                      • [ICD-11: 2B91]
                                                                                                                                                      • [ICD-11: 2C12]
                                                                                                                                                      • [ICD-11: 2A80-2A86]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 4Q15746MYLKT97141Clinical trial target
                                                                                                                                                      • Duodenal ulcer
                                                                                                                                                      • [ICD-11: DA63]
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 5O43781DYRK3T97149Patented-recorded Target
                                                                                                                                                        6Q13535ATRT97155Clinical trial target
                                                                                                                                                      • Lung cancer
                                                                                                                                                      • Lymphoma
                                                                                                                                                      • Mature B-cell leukaemia
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2A80-2A86]
                                                                                                                                                      • [ICD-11: 2A82]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 7Q13315ATMT97196Clinical trial target
                                                                                                                                                      • Brain cancer
                                                                                                                                                      • Lung cancer
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2A00]
                                                                                                                                                      • [ICD-11: 2C25]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 8P01137TGFB1T97257Successful Target
                                                                                                                                                      • Idiopathic interstitial pneumonitis
                                                                                                                                                      • [ICD-11: CB03]
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • 9Q16831UPP1T97388Literature-reported Target
                                                                                                                                                      • Nasopharyngitis
                                                                                                                                                      • [ICD-11: CA00]
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • 10Q9UIQ6LNPEPT97537Patented-recorded Target
                                                                                                                                                        11P13612ITGA4T97587Successful Target
                                                                                                                                                      • Crohn disease
                                                                                                                                                      • Multiple sclerosis
                                                                                                                                                      • Ulcerative colitis
                                                                                                                                                      • [ICD-11: DD70]
                                                                                                                                                      • [ICD-11: 8A40]
                                                                                                                                                      • [ICD-11: DD71]
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 12Q99683MAP3K5T97589Clinical trial target
                                                                                                                                                      • Chronic kidney disease
                                                                                                                                                      • Pulmonary hypertension
                                                                                                                                                      • [ICD-11: GB61]
                                                                                                                                                      • [ICD-11: BB01]
                                                                                                                                                      • Diseases of the genitourinary system
                                                                                                                                                      • Diseases of the circulatory system
                                                                                                                                                      • 13Q9UQB9AURKCT97592Clinical trial target
                                                                                                                                                      • Malignant haematopoietic neoplasm
                                                                                                                                                      • Prostate cancer
                                                                                                                                                      • Solid tumour/cancer
                                                                                                                                                      • [ICD-11: 2B33]
                                                                                                                                                      • [ICD-11: 2C82]
                                                                                                                                                      • [ICD-11: 2A00-2F9Z]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 14P48039MTNR1AT97613Successful Target
                                                                                                                                                      • Insomnia
                                                                                                                                                      • [ICD-11: 7A00-7A0Z]
                                                                                                                                                      • Sleep-wake disorders
                                                                                                                                                      • 15Q06187BTKT97719Target
                                                                                                                                                      • Leukaemia
                                                                                                                                                      • [ICD-11: 2A60-2B33]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 16P16519PCSK2T97749Literature-reported Target
                                                                                                                                                        17Q9NYE9HCCS4T97821Literature-reported Target
                                                                                                                                                        18P51686CCR9T97873Clinical trial target
                                                                                                                                                      • Crohn disease
                                                                                                                                                      • [ICD-11: DD70]
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 19Q96DB2HDAC11T97903Patented-recorded Target
                                                                                                                                                        20P25090FPR2T97917Literature-reported Target
                                                                                                                                                      • Alzheimer disease
                                                                                                                                                      • [ICD-11: 8A20]
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • 21Q96IY4CPB2T98022Clinical trial target
                                                                                                                                                      • Cerebral ischaemia
                                                                                                                                                      • Cerebral ischaemic stroke
                                                                                                                                                      • Thrombosis
                                                                                                                                                      • [ICD-11: 8B1Z]
                                                                                                                                                      • [ICD-11: 8B11]
                                                                                                                                                      • [ICD-11: DB61-GB90]
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the nervous system
                                                                                                                                                      • Diseases of the digestive system
                                                                                                                                                      • 22Q9BWU1CDK19T98034Clinical trial target
                                                                                                                                                      • Acute myeloid leukaemia
                                                                                                                                                      • Myelodysplastic syndrome
                                                                                                                                                      • [ICD-11: 2A60]
                                                                                                                                                      • [ICD-11: 2A37]
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • Neoplasms
                                                                                                                                                      • 23O95822MLYCDT98078Literature-reported Target
                                                                                                                                                        24Q9NQS5GPR84T98091Clinical trial target
                                                                                                                                                      • Idiopathic interstitial pneumonitis
                                                                                                                                                      • Type 2 diabetes mellitus
                                                                                                                                                      • [ICD-11: CB03]
                                                                                                                                                      • [ICD-11: 5A11]
                                                                                                                                                      • Diseases of the respiratory system
                                                                                                                                                      • Endocrine, nutritional or metabolic diseases
                                                                                                                                                      • 25Q9H1R3MYLK2T98198Literature-reported Target