S.no. Gene Symbol Function HGNC ID Chromosome Chromosome Start Chromosome End Strand ENSEMBL ID PMID
1 ABCB1 Folate transport407q21.128713317987342639-1ENSG00000085563Williams.et.al
2 ABCC1 Folate transport5116p13.116043434162369301ENSG0000010322215041471
3 ABCC2 Cellular export of natural folates5310q241015424631016116621ENSG0000002383920386493
4 AHCY Adenosylhomocysteinase34320q11.223286807132891215-1ENSG0000010144421765920
5 ALDH1L1 Distribution of one carbon units39783q21.2125822404125900029-1ENSG0000014490821765920
6 AMPD1 Purine biosynthesis DNA synthesis4681p13115215720115238239-1ENSG0000011674819902562
7 AMT Distribution of one carbon units glycine cleavage4733p21.314945421149460111-1ENSG0000014502021765920
8 ATIC Purine biosynthesis - DNA synthesis7942q352161766792162144961ENSG0000013836321765920
9 BHMT Homocysteine remethylation10475q14.178407604784281131ENSG0000014569221765920
10 CBS catalyse the formation of hydrogen sulfide155021q22.34447330144496472-1ENSG0000016020017548676
11 CD320 Vitamin B12 cellular receptor 1669219p13.3-p13.283670118373240-1ENSG0000016777521765920
12 CUBN Vitamin B12 intestinal receptor 254810p121686596517171816-1ENSG0000010761121765920
13 DHFR Folate homeostasis 28615q14.17992204579950800-1ENSG0000022871621765920
14 DMGDH Distribution of one 244755q14.17829342978365449-1ENSG0000013283721765920
15 DNMT1 DNA methylation 297619p13.21024402210305755-1ENSG0000013081621765920
16 DNMT3A DNA methylation 29782p232545583025564784-1ENSG0000011977221765920
17 DNMT3B DNA methylation 297920q11.231350191313971621ENSG0000008830521765920
18 FOLH1 Folate hydrolysis (intestinal) 378811p11.24916818749230222-1ENSG0000008620521765920
19 FOLR1 Cellular folate uptake 379111q13.3-q14.171900602719073671ENSG0000011019521765920
20 FPGS Folate homeostasis38249q34.111305651541305765561ENSG0000013687721765920
21 FTCD Provision of one-carbon units 397421q22.34755617647575481-1ENSG0000016028221765920
22 GART Purine biosynthesis DNA synthesis 416321q22.113487623834914464-1ENSG0000026247321765920
23 GGH Folate hydrolysis (lysosomal)42488q12.36392763963951610-1ENSG0000013756321765920
24 GIF B12 absorbtion 426811q12.15959674659612974-1ENSG0000013481221765920
25 GNMT Glycine methylation 44156p1242928500429316181ENSG0000012471321765920
26 ITPA Hydrolyzes non-canonical purine to their respective monophosphate derivatives617620p319000632045161ENSG0000012587722838948
27 MAT1A Synthesis of SAM - methylation 690310q228203157682049434-1ENSG0000015122421765920
28 MAT2A Synthesis of SAM - methylation 69042p11.285766101857724031ENSG0000016890621765920
29 MAT2B Synthesis of SAM - methylation69055q341629325341629463591ENSG0000003827421765920
30 MMAB B12 metabolism 1933112q240991521""110011
31 MTFMT Mitochondrial protein synthesis 2966615q22.316529385065321977-1ENSG0000010370721765920
32 MTHFD1 distribution of one carbon unit743214q2464854759649267251ENSG0000010071421765920
33 MTHFD1L distribution of one carbon unit210556q25.11511868151514230231ENSG0000012025421765920
34 MTHFD2 distribution of one carbon unit74342p13.174425690744424241ENSG0000006591121765920
35 MTHFD2L distribution of one carbon unit318654q13.375023829751688141ENSG0000016373821765920
36 MTHFR distribution of one carbon unit74361p36.31184578711866160-1ENSG0000017700021765920
37 MTHFS distribution of one carbon unit743715q24.38013588980189391-1ENSG0000013637121765920
38 MTR Homocysteine remethylation 318651q432369585812370672811ENSG0000011698421765920
39 MTRR Homocysteine remethylation 74365p15.31786921779012351ENSG0000012427521765920
40 SARDH distribution of one carbon unit105369q33-q34136528684136603479-1ENSG0000012345321765920
41 SHMT1 Provision of one-carbon units 1085017p11.21823118718266856-1ENSG0000017697421765920
42 SHMT2 Provision of one-carbon units 1085212q12-q1457623356576287181ENSG0000018219921765920
43 SLC19A1 Reduced folate carrier 1093721q22.34693462946962385-1ENSG0000017363821765920
44 SLC25A32 Mitochondrial folate transporter298638q22.3104410866104427563-1ENSG0000016493321765920
45 SLC46A1 Proton coupled folate transporter 3052117q11.22672166126733230-1ENSG0000026218621765920
46 TCN1 B12 transport protein116211q11-q125962028159634041-1ENSG0000013482721765920
47 TCN2 B12 transport protein1165322q12.231003070310230471ENSG0000018533921765920
48 TYMS Thymidylate biosynthesis 1244118p11.31-p11.216576046734991ENSG0000017689021765920